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Combined dabrafenib and trametinib treatment in a case of chemotherapy-refractory extrahepatic BRAF V600E mutant cholangiocarcinoma: dramatic clinical and radiological response with a confusing synchronic new liver lesion

Since the prognosis of advanced cholangiocarcinoma (CCA) remains poor with traditional chemotherapy, attention has shifted to molecularly targeted agents. Results of available clinical studies reveal little or no benefit of using targeted agents in advanced CCA. Limitations of these trials could be...

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Detalhes bibliográficos
Publicado no:J Gastrointest Oncol
Main Authors: Kocsis, Judit, Árokszállási, Anita, András, Csilla, Balogh, Ingrid, Béres, Edit, Déri, Júlia, Peták, István, Jánváry, Levente, Horváth, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401859/
https://ncbi.nlm.nih.gov/pubmed/28480077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2017.01.06
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