Human Cytomegalovirus Vaccine Based on the Envelope gH/gL Pentamer Complex

Human Cytomegalovirus (HCMV) utilizes two different pathways for host cell entry. HCMV entry into fibroblasts requires glycoproteins gB and gH/gL, whereas HCMV entry into epithelial and endothelial cells (EC) requires an additional complex composed of gH, gL, UL128, UL130, and UL131A, referred to as...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Wussow, Felix, Chiuppesi, Flavia, Martinez, Joy, Campo, John, Johnson, Erica, Flechsig, Christin, Newell, Maegan, Tran, Elaine, Ortiz, Jose, La Rosa, Corinna, Herrmann, Andreas, Longmate, Jeff, Chakraborty, Rana, Barry, Peter A., Diamond, Don J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239111/
https://ncbi.nlm.nih.gov/pubmed/25412505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004524
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