Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

During Ebola virus (EBOV) infection a significant amount of surface glycoprotein GP is shed from infected cells in a soluble form due to cleavage by cellular metalloprotease TACE. Shed GP and non-structural secreted glycoprotein sGP, both expressed from the same GP gene, have been detected in the bl...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Escudero-Pérez, Beatriz, Volchkova, Valentina A., Dolnik, Olga, Lawrence, Philip, Volchkov, Viktor E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239094/
https://ncbi.nlm.nih.gov/pubmed/25412102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004509
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