Indoleamine 2,3-Dioxygenase Controls Fungal Loads and Immunity in Paracoccidioidomicosis but is More Important to Susceptible than Resistant Hosts

BACKGROUND: Paracoccidioidomycosis, a primary fungal infection restricted to Latin America, is acquired by inhalation of fungal particles. The immunoregulatory mechanisms that control the severe and mild forms of paracoccidioidomycosis are still unclear. Indoleamine 2,3-dioxygenase (IDO), an IFN-γ i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Araújo, Eliseu F., Loures, Flávio V., Bazan, Silvia B., Feriotti, Claudia, Pina, Adriana, Schanoski, Alessandra S., Costa, Tânia A., Calich, Vera L. G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238999/
https://ncbi.nlm.nih.gov/pubmed/25411790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003330
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