Indoleamine 2,3-Dioxygenase Controls Fungal Loads and Immunity in Paracoccidioidomicosis but is More Important to Susceptible than Resistant Hosts

BACKGROUND: Paracoccidioidomycosis, a primary fungal infection restricted to Latin America, is acquired by inhalation of fungal particles. The immunoregulatory mechanisms that control the severe and mild forms of paracoccidioidomycosis are still unclear. Indoleamine 2,3-dioxygenase (IDO), an IFN-γ i...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Araújo, Eliseu F., Loures, Flávio V., Bazan, Silvia B., Feriotti, Claudia, Pina, Adriana, Schanoski, Alessandra S., Costa, Tânia A., Calich, Vera L. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238999/
https://ncbi.nlm.nih.gov/pubmed/25411790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003330
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