Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii

Lipid bodies [lipid droplets (LBs)] are lipid-rich organelles involved in lipid metabolism, signalling and inflammation. Recent findings suggest a role for LBs in host response to infection; however, the potential functions of this organelle in Toxoplasma gondii infection and how it alters macrophag...

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Détails bibliographiques
Publié dans:Mem Inst Oswaldo Cruz
Auteurs principaux: Mota, Laura Azeredo Miranda, Roberto, João, Monteiro, Verônica Gomes, Lobato, Caroliny Samary Silva, de Oliveira, Marco Antonio, da Cunha, Maura, D’Ávila, Heloisa, Seabra, Sérgio Henrique, Bozza, Patrícia Torres, DaMatta, Renato Augusto
Format: Artigo
Langue:Inglês
Publié: Instituto Oswaldo Cruz, Ministério da Saúde 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238769/
https://ncbi.nlm.nih.gov/pubmed/25317704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-0276140119
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