Inactivation of chromatin remodeling factors sensitizes cells to selective cytotoxic stress

The SWI/SNF chromatin-remodeling complex plays an essential role in several cellular processes including cell proliferation, differentiation, and DNA repair. Loss of normal function of the SWI/SNF complex because of mutations in its subunits correlates with tumorigenesis in humans. For many of these...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biologics
Main Authors: Freeman, Miles D, Mazu, Tryphon, Miles, Jana S, Darling-Reed, Selina, Flores-Rozas, Hernan
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238754/
https://ncbi.nlm.nih.gov/pubmed/25484574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S67046
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