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Pharmacokinetics of Tedizolid Following Oral Administration: Single and Multiple Dose, Effect of Food, and Comparison of Two Solid Forms of the Prodrug

OBJECTIVES: The single- and multiple-dose pharmacokinetics (PK) of tedizolid were examined after oral administration of tedizolid phosphate disodium (TPD), including the effect of food on PK. The relative bioavailability of TPD to the free acid tedizolid phosphate was determined to bridge the result...

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Bibliografiske detaljer
Udgivet i:Pharmacotherapy
Main Authors: Flanagan, Shawn D, Bien, Paul A, Muñoz, Kelly A, Minassian, Sonia L, Prokocimer, Philippe G
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238735/
https://ncbi.nlm.nih.gov/pubmed/23926058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1337
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