Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells

Heat shock protein 90 (Hsp90) is constitutively expressed at 2-10-fold higher levels in tumor cells compared to normal cells, suggesting that it may be critically important for tumor cell growth and survival. These features make Hsp90 a potential target for anticancer drug development. Inhibition of...

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Bibliografske podrobnosti
izdano v:Int J Oncol
Main Authors: MORI, MASAKI, HITORA, TOSHIAKI, NAKAMURA, OSAMU, YAMAGAMI, YOSHIKI, HORIE, RYOSUKE, NISHIMURA, HIDEKI, YAMAMOTO, TETSUJI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238730/
https://ncbi.nlm.nih.gov/pubmed/25351442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2727
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