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The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells
The inhibition of the mammalian target of rapamycin (mTOR) signaling pathway promotes the initiation of autophagy, and the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated protein kinase (ERK) is well known to induce autophagy. Autophagy is a self-defense mechanism of cancer ce...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055350/ https://ncbi.nlm.nih.gov/pubmed/24676456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1715 |
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