The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells

The inhibition of the mammalian target of rapamycin (mTOR) signaling pathway promotes the initiation of autophagy, and the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated protein kinase (ERK) is well known to induce autophagy. Autophagy is a self-defense mechanism of cancer ce...

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Detalhes bibliográficos
Main Authors: NAKAMURA, OSAMU, HITORA, TOSHIAKI, YAMAGAMI, YOSHIKI, MORI, MASAKI, NISHIMURA, HIDEKI, HORIE, RYOSUKE, YAMAGUCHI, KONOSUKE, YAMAMOTO, TETSUJI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055350/
https://ncbi.nlm.nih.gov/pubmed/24676456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1715
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