Sheathless Capillary Electrophoresis-Tandem Mass Spectrometry for Top-Down Characterization of Pyrococcus furiosus Proteins on a Proteome Scale

[Image: see text] Intact protein analysis via top-down mass spectrometry (MS) provides the unique capability of fully characterizing protein isoforms and combinatorial post-translational modifications (PTMs) compared to the bottom-up MS approach. Front-end protein separation poses a challenge for an...

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Vydáno v:Anal Chem
Hlavní autoři: Han, Xuemei, Wang, Yueju, Aslanian, Aaron, Bern, Marshall, Lavallée-Adam, Mathieu, Yates, John R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238646/
https://ncbi.nlm.nih.gov/pubmed/25346219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac503439n
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