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H3K27me and PRC2 transmit a memory of repression across generations and during development
For proper development, cells must retain patterns of gene expression and repression through cell division. Repression via methylation of histone H3 on Lys27 (H3K27me) by Polycomb repressive complex 2 (PRC2) is conserved, but its transmission is not well understood. Our studies suggest that PRC2 rep...
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| Publicado no: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4238426/ https://ncbi.nlm.nih.gov/pubmed/25237104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1255023 |
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