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Diverse modes of evolutionary emergence and flux of conserved microRNA clusters

Many animal miRNA loci reside in genomic clusters that generate multicistronic primary-miRNA transcripts. While clusters that contain copies of the same miRNA hairpin are clearly products of local duplications, the evolutionary provenance of clusters with disparate members is less clear. Recently, i...

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Détails bibliographiques
Publié dans:RNA
Auteurs principaux: Mohammed, Jaaved, Siepel, Adam, Lai, Eric C.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238352/
https://ncbi.nlm.nih.gov/pubmed/25332374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.046805.114
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