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Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas.
To test whether insulin secretion is self-regulatory, canine pancreata were isolated and perfused in vitro and were infused with 0.3, 0.6, or 1.2 mU/ml exogenous insulin. Basal and arginine-stimulated concentrations of C-peptide, glucagon, and somatostatin were measured. There were no significant di...
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| Опубликовано в: : | J Clin Invest |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
1986
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2877010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112702 |
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