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Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas.

To test whether insulin secretion is self-regulatory, canine pancreata were isolated and perfused in vitro and were infused with 0.3, 0.6, or 1.2 mU/ml exogenous insulin. Basal and arginine-stimulated concentrations of C-peptide, glucagon, and somatostatin were measured. There were no significant di...

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Detalhes bibliográficos
Main Authors: Stagner, J, Samols, E, Polonsky, K, Pugh, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC423804/
https://ncbi.nlm.nih.gov/pubmed/2877010
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