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Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors

BACKGROUND: Histamine (HA) regulates the sleep-wake cycle, synaptic plasticity and memory in adult mammals. Dopaminergic specification in the embryonic ventral midbrain (VM) coincides with increased HA brain levels. To study the effect of HA receptor stimulation on dopamine neuron generation, we adm...

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Bibliografische gegevens
Gepubliceerd in:Mol Brain
Hoofdauteurs: Escobedo-Avila, Itzel, Vargas-Romero, Fernanda, Molina-Hernández, Anayansi, López-González, Rodrigo, Cortés, Daniel, De Carlos, Juan A, Velasco, Iván
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237960/
https://ncbi.nlm.nih.gov/pubmed/25112718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-014-0058-x
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