Organoid cultures derived from patients with advanced prostate cancer

The lack of in vitro prostate cancer models that recapitulate the diversity of human prostate cancer has hampered progress in understanding disease pathogenesis and therapy response. Using a 3D “organoid” system, we report success in long-term culture of prostate cancer from biopsy specimens and cir...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Gao, Dong, Vela, Ian, Sboner, Andrea, Iaquinta, Phil J., Karthaus, Wouter R., Gopalan, Anuradha, Dowling, Catherine, Wajala, Jackie N., Undvall, Eva A., Arora, Vivek K., Wongvipat, John, Kossai, Myriam, Ramazanoglu, Sinan, Barboza, Luendreo P., Di, Wei, Cao, Zhen, Zhang, Qi Fan, Sirota, Inna, Ran, Leili, MacDonald, Theresa Y., Beltran, Himisha, Mosquera, Juan-Miguel, Touijer, Karim A., Scardino, Peter T., Laudone, Vincent P., Curtis, Kristen R., Rathkopf, Dana E., Morris, Michael J., Danila, Daniel C., Slovin, Susan F., Solomon, Stephen B., Eastham, James A., Chi, Ping, Carver, Brett, Rubin, Mark A., Scher, Howard I., Clevers, Hans, Sawyers, Charles L., Chen, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237931/
https://ncbi.nlm.nih.gov/pubmed/25201530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.08.016
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