A defect in the regulation of major histocompatibility complex class II gene expression in human HLA-DR negative lymphocytes from patients with combined immunodeficiency syndrome.

Patients with an autosomal recessive combined immunodeficiency are characterized by an HLA negative phenotype of activated T and B lymphocytes. To determine the molecular basis of this syndrome we have studied the biosynthesis of class I and II antigens and the expression of relevant genes in these...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lisowska-Grospierre, B, Charron, D J, de Préval, C, Durandy, A, Griscelli, C, Mach, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3860509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111974
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