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Inherited immunodeficiency with a defect in a major histocompatibility complex class II promoter-binding protein differs in the chromatin structure of the HLA-DRA gene.

A defect in a trans-regulatory factor which controls major histocompatibility complex class II gene expression is responsible for an inherited form of immunodeficiency with a lack of expression of human leukocyte antigen (HLA) class II antigens. We have recently described and cloned an HLA class II...

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Autors principals: Gönczy, P, Reith, W, Barras, E, Lisowska-Grospierre, B, Griscelli, C, Hadam, M R, Mach, B
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC362172/
https://ncbi.nlm.nih.gov/pubmed/2467188
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