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The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters.

The X box of major histocompatibility complex class II promoters is essential for proper expression of class II genes. Here we show that two distinct protein-DNA complexes (A and B), which exhibit similar binding characteristics and identical contact points on the X box, can be formed. This suggests...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Herrero Sanchez, C, Reith, W, Silacci, P, Mach, B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC360302/
https://ncbi.nlm.nih.gov/pubmed/1508204
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