Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial

BACKGROUND: Germ cell tumors (GCT) are the most common solid tumors in adolescent and young adult males (age 15 and 35 years) and remain one of the most curable of all solid malignancies. However a subset of patients will have tumors that are refractory to standard chemotherapy agents. The managemen...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Subbiah, Vivek, Meric-Bernstam, Funda, Mills, Gordon B, Shaw, Kenna R Mills, Bailey, Ann Marie, Rao, Priya, Ward, John F, Pagliaro, Lance C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237879/
https://ncbi.nlm.nih.gov/pubmed/25085632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0052-x
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