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N-3 polyunsaturated fatty acids decrease levels of doxorubicin-induced reactive oxygen species in cardiomyocytes -- involvement of uncoupling protein UCP2

BACKGROUND: Use of the chemotherapeutic drug doxorubicin (DOX) is associated with serious cardiotoxicity, as it increases levels of reactive oxygen species (ROS). N-3 polyunsaturated fatty acid dietary supplements can be of benefit to patients undergoing cancer therapy. The aims of this study were t...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Hsu, Hsiu-Ching, Chen, Ching-Yi, Chen, Ming-Fong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237738/
https://ncbi.nlm.nih.gov/pubmed/25407516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-014-0101-3
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