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Cationic surface charge enhances early regional deposition of liposomes after intracarotid injection

Rapid first pass uptake of drugs is necessary to increase tissue deposition after intraarterial (IA) injection. Here we tested whether brain tissue deposition of a nanoparticulate liposomal carrier could be enhanced by coordinated manipulation of liposome surface charge and physiological parameters,...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Joshi, Shailendra, Singh-Moon, Rajinder, Wang, Mei, Chaudhuri, Durba B., Ellis, Jason A., Bruce, Jeffrey N., Bigio, Irving J., Straubinger, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237707/
https://ncbi.nlm.nih.gov/pubmed/25195130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1584-1
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