Hepatitis C Virus Nonstructural Protein 5A Inhibits Thapsigargin-Induced Apoptosis

BACKGROUND: We previously reported that the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) down-regulates TLR4 signaling and lipopolysaccharide-induced apoptosis of hepatocytes. There have been several reports regarding the association between HCV infection and endoplasmic reticulum (ER) st...

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Bibliographic Details
Published in:PLoS One
Main Authors: Jiang, Xia, Kanda, Tatsuo, Wu, Shuang, Nakamoto, Shingo, Wakita, Takaji, Shirasawa, Hiroshi, Yokosuka, Osamu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237446/
https://ncbi.nlm.nih.gov/pubmed/25409163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113499
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