Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-κB-Nuclear Translocation

BACKGROUND: Hepatitis C virus (HCV) infection is one of the major causes of cirrhosis and hepatocellular carcinoma. HCV nonstructural protein 5A (NS5A) is an attractive antiviral target and plays an important role in HCV replication as well as hepatocarcinogenesis. The aim of this study was to asses...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jiang, Xia, Kanda, Tatsuo, Wu, Shuang, Nakamoto, Shingo, Nakamura, Masato, Sasaki, Reina, Haga, Yuki, Wakita, Takaji, Shirasawa, Hiroshi, Yokosuka, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489642/
https://ncbi.nlm.nih.gov/pubmed/26133378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131973
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