A Candidate Gene Approach Identifies an IL33 Genetic Variant as a Novel Genetic Risk Factor for GCA

INTRODUCTION: Increased expression of IL-33 and its receptor ST2, encoded by the IL1RL1 gene, has been detected in the inflamed arteries of giant cell arteritis (GCA) patients. The aim of the present study was to investigate for the first time the potential influence of the IL33 and IL1RL1 loci on G...

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Publicado no:PLoS One
Main Authors: Márquez, Ana, Solans, Roser, Hernández-Rodríguez, José, Cid, Maria C., Castañeda, Santos, Ramentol, Marc, Rodriguez-Rodriguez, Luis, Narváez, Javier, Blanco, Ricardo, Ortego-Centeno, Norberto, Palm, Øyvind, Diamantopoulos, Andreas P., Braun, Niko, Moosig, Frank, Witte, Torsten, Beretta, Lorenzo, Lunardi, Claudio, Cimmino, Marco A., Vaglio, Augusto, Salvarani, Carlo, González-Gay, Miguel A., Martín, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237421/
https://ncbi.nlm.nih.gov/pubmed/25409453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113476
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