A Candidate Gene Approach Identifies an IL33 Genetic Variant as a Novel Genetic Risk Factor for GCA

INTRODUCTION: Increased expression of IL-33 and its receptor ST2, encoded by the IL1RL1 gene, has been detected in the inflamed arteries of giant cell arteritis (GCA) patients. The aim of the present study was to investigate for the first time the potential influence of the IL33 and IL1RL1 loci on G...

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Vydáno v:PLoS One
Hlavní autoři: Márquez, Ana, Solans, Roser, Hernández-Rodríguez, José, Cid, Maria C., Castañeda, Santos, Ramentol, Marc, Rodriguez-Rodriguez, Luis, Narváez, Javier, Blanco, Ricardo, Ortego-Centeno, Norberto, Palm, Øyvind, Diamantopoulos, Andreas P., Braun, Niko, Moosig, Frank, Witte, Torsten, Beretta, Lorenzo, Lunardi, Claudio, Cimmino, Marco A., Vaglio, Augusto, Salvarani, Carlo, González-Gay, Miguel A., Martín, Javier
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237421/
https://ncbi.nlm.nih.gov/pubmed/25409453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113476
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