Fetal Alcohol Exposure Alters Proopiomelanocortin Gene Expression and Hypothalamic-Pituitary-Adrenal Axis Function via Increasing MeCP2 Expression in the Hypothalamus

Proopiomelanocortin (POMC) is a precursor gene of the neuropeptide β-endorphin in the hypothalamus and is known to regulate various physiological functions including stress response. Several recent reports showed that fetal alcohol exposure programs the hypothalamus to produce lower levels of POMC g...

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Bibliographic Details
Published in:PLoS One
Main Authors: Gangisetty, Omkaram, Bekdash, Rola, Maglakelidze, George, Sarkar, Dipak K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237387/
https://ncbi.nlm.nih.gov/pubmed/25409090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113228
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