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Hypermethylation of proopiomelanocortin and period 2 genes in blood are associated with greater subjective and behavioral motivation for alcohol in humans

BACKGROUND: Epigenetic modifications of a gene have been shown to play a role in maintaining a long-lasting change in gene expression. We hypothesize that alcohol’s modulating effect on DNA methylation on certain genes in blood is evident in binge and heavy alcohol drinkers and is associated with al...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Gangisetty, Omkaram, Sinha, Rajita, Sarkar, Dipak K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370509/
https://ncbi.nlm.nih.gov/pubmed/30597578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13932
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