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Genome Editing in Mouse Spermatogonial Stem/Progenitor Cells Using Engineered Nucleases
Editing the genome to create specific sequence modifications is a powerful way to study gene function and promises future applicability to gene therapy. Creation of precise modifications requires homologous recombination, a very rare event in most cell types that can be stimulated by introducing a d...
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Publicat a: | PLoS One |
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Autors principals: | , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science
2014
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237364/ https://ncbi.nlm.nih.gov/pubmed/25409432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112652 |
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