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Pharmacological Activation of the EDA/EDAR Signaling Pathway Restores Salivary Gland Function following Radiation-Induced Damage

Radiotherapy of head and neck cancers often results in collateral damage to adjacent salivary glands associated with clinically significant hyposalivation and xerostomia. Due to the reduced capacity of salivary glands to regenerate, hyposalivation is treated by substitution with artificial saliva, r...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Hill, Grace, Headon, Denis, Harris, Zoey I., Huttner, Kenneth, Limesand, Kirsten H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237357/
https://ncbi.nlm.nih.gov/pubmed/25409170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112840
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