Distinct Impacts of Eda and Edar Loss of Function on the Mouse Dentition

BACKGROUND: The Eda-A1-Edar signaling pathway is involved in the development of organs with an ectodermal origin, including teeth. In mouse, mutants are known for both the ligand, Eda-A1 (Tabby), and the receptor, Edar (Downless). The adult dentitions of these two mutants have classically been consi...

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Bibliografiske detaljer
Main Authors: Charles, Cyril, Pantalacci, Sophie, Tafforeau, Paul, Headon, Denis, Laudet, Vincent, Viriot, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659790/
https://ncbi.nlm.nih.gov/pubmed/19340299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004985
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