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Comparison of Results from Different Imputation Techniques for Missing Data from an Anti-Obesity Drug Trial

BACKGROUND: In randomised trials of medical interventions, the most reliable analysis follows the intention-to-treat (ITT) principle. However, the ITT analysis requires that missing outcome data have to be imputed. Different imputation techniques may give different results and some may lead to bias....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jørgensen, Anders W., Lundstrøm, Lars H., Wetterslev, Jørn, Astrup, Arne, Gøtzsche, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237333/
https://ncbi.nlm.nih.gov/pubmed/25409438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111964
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