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Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway

Leukemia is a leading cause of cancer death. Recently, the latexin (Lxn) gene was identified as a potential tumor suppressor in several types of solid tumors and lymphoma, and Lxn expression was found to be absent or downregulated in leukemic cells. Whether Lxn functions as a tumor suppressor in leu...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: You, Y, Wen, R, Pathak, R, Li, A, Li, W, St Clair, D, Hauer-Jensen, M, Zhou, D, Liang, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237263/
https://ncbi.nlm.nih.gov/pubmed/25341047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.443
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