HDAC8 and STAT3 repress BMF gene activity in colon cancer cells

Histone deacetylase (HDAC) inhibitors are undergoing clinical trials as anticancer agents, but some exhibit resistance mechanisms linked to anti-apoptotic Bcl-2 functions, such as BH3-only protein silencing. HDAC inhibitors that reactivate BH3-only family members might offer an improved therapeutic...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Kang, Y, Nian, H, Rajendran, P, Kim, E, Dashwood, W M, Pinto, J T, Boardman, L A, Thibodeau, S N, Limburg, P J, Löhr, C V, Bisson, W H, Williams, D E, Ho, E, Dashwood, R H
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237248/
https://ncbi.nlm.nih.gov/pubmed/25321483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.422
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы