Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly

BACKGROUND: Histone deacetylase (HDAC) inhibitors are currently undergoing clinical evaluation as anti-cancer agents. Dietary constituents share certain properties of HDAC inhibitor drugs, including the ability to induce global histone acetylation, turn-on epigenetically-silenced genes, and trigger...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rajendran, Praveen, Delage, Barbara, Dashwood, W Mohaiza, Yu, Tian-Wei, Wuth, Bradyn, Williams, David E, Ho, Emily, Dashwood, Roderick H
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127849/
https://ncbi.nlm.nih.gov/pubmed/21624135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-68
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires