Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow cultures.

Transforming growth factor-alpha (TGF-alpha) is synthesized by a variety of tumor cell lines and stimulates osteoclastic bone resorption in vitro. The mechanism by which TGF-alpha increases osteoclast activity is unknown. We used a human marrow culture system that forms osteoclast-like multinucleate...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Clin Invest
Autori principali:	Takahashi, N, MacDonald, B R, Hon, J, Winkler, M E, Derynck, R, Mundy, G R, Roodman, G D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3489738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112677
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!