1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow.

1,25-Dihydroxyvitamin D3 induces cells derived from mononuclear phagocytes such as HL-60 and U937 to differentiate to macrophage-like cells and causes alveolar macrophages to form multinucleated cells in vitro. Since the osteoclast is thought to be derived from early marrow cells of the macrophage l...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Roodman, G D, Ibbotson, K J, MacDonald, B R, Kuehl, T J, Mundy, G R
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1985
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391473/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3865222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.8213
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