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Polyadenylylation helps regulate mRNA decay in Escherichia coli.

As part of our genetic analysis of mRNA decay in Escherichia coli K-12, we examined the effect of the pcnB gene [encoding poly(A) polymerase I] on message stability. Eliminating poly(A) polymerase I (delta pcnB) dramatically stabilized the lpp, ompA, and trxA transcripts. The half-lives of individua...

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Bibliografiske detaljer
Main Authors: O'Hara, E B, Chekanova, J A, Ingle, C A, Kushner, Z R, Peters, E, Kushner, S R
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC42371/
https://ncbi.nlm.nih.gov/pubmed/7534403
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