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The emerging role of speckle-type POZ protein (SPOP) in cancer development
Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is an E3 ubiquitin ligase adaptor protein that is frequently mutated in prostate and endometrial cancers. All the cancer-associated SPOP mutations reported to date are clustered in the meprin and TRAF homology (MATH) domain, presuma...
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| Pubblicato in: | Drug Discov Today |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237012/ https://ncbi.nlm.nih.gov/pubmed/25058385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.07.009 |
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