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Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65

Glycyrrhizic acid (GA) is a natural product with favorable antitumor activity. But, glycyrrhetinic acid monoglucuronide (GAMG) showed stronger antitumor activity than GA. It is of our interest to generate and identify novel compounds with regulation telomerase for cancer therapy. So, in this study,...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Tang, Wen-jian, Yang, Yong-an, Xu, He, Shi, Jing-bo, Liu, Xin-hua
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236752/
https://ncbi.nlm.nih.gov/pubmed/25407586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07106
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