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Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3.3
The centromere-specific histone H3 variant, CENP-A, is overexpressed in particular aggressive cancer cells, where it can be mislocalized ectopically in the form of heterotypic nucleosomes containing H3.3. In the present study, we report the crystal structure of the heterotypic CENP-A/H3.3 particle a...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236741/ https://ncbi.nlm.nih.gov/pubmed/25408271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07115 |
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