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Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast

BACKGROUND: The regulatory mechanism of recombination is one of the most fundamental problems in genomics, with wide applications in genome wide association studies (GWAS), birth-defect diseases, molecular evolution, cancer research, etc. Recombination events cluster into short genomic regions calle...

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Veröffentlicht in:BMC Syst Biol
Hauptverfasser: Wu, Min, Kwoh, Chee-Keong, Li, Xiaoli, Zheng, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236725/
https://ncbi.nlm.nih.gov/pubmed/25208583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0107-1
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