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LDsplit: screening for cis-regulatory motifs stimulating meiotic recombination hotspots by analysis of DNA sequence polymorphisms

BACKGROUND: As a fundamental genomic element, meiotic recombination hotspot plays important roles in life sciences. Thus uncovering its regulatory mechanisms has broad impact on biomedical research. Despite the recent identification of the zinc finger protein PRDM9 and its 13-mer binding motif as ma...

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Autori principali: Yang, Peng, Wu, Min, Guo, Jing, Kwoh, Chee Keong, Przytycka, Teresa M, Zheng, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936957/
https://ncbi.nlm.nih.gov/pubmed/24533858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-48
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