Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities.

The study of the Ig variable region heavy chain (VH) genes used to encode antibodies specific for self-epitopes from murine hybridomas showed that three VH families are primarily utilized: VH J558, the largest family, and VH QPC52 and VH 7183, the families most proximal to the Ig joining region heav...

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Pubblicato in:	J Clin Invest
Autori principali:	Monestier, M, Manheimer-Lory, A, Bellon, B, Painter, C, Dang, H, Talal, N, Zanetti, M, Schwartz, R, Pisetsky, D, Kuppers, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423668/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2427543/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112637
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