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A Phase II trial of axitinib in patients with various histologic subtypes of advanced thyroid cancer: long-term outcomes and pharmacokinetic/pharmacodynamic analyses

PURPOSE: Axitinib, a potent and selective second-generation inhibitor of vascular endothelial growth factor receptors, has shown activity in advanced thyroid cancer in a Phase II study. We report updated overall survival and pharmacokinetic/pharmacodynamic (PK/PD) analyses from the study. METHODS: P...

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Publicat a:Cancer Chemother Pharmacol
Autors principals: Cohen, E. E. W., Tortorici, M., Kim, S., Ingrosso, A., Pithavala, Y. K., Bycott, P.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236619/
https://ncbi.nlm.nih.gov/pubmed/25315258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2604-8
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