Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.

Synovial fluid mononuclear cells (SFMC) from patients with active rheumatoid arthritis characteristically respond poorly to mitogens. In this study, mitogenic antibodies reactive with the CD3(T3) antigen on human T lymphocytes were used to analyze the basis for the deficiency. OKT3-induced prolifera...

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Pubblicato in:	J Clin Invest
Autori principali:	Lotz, M, Tsoukas, C D, Robinson, C A, Dinarello, C A, Carson, D A, Vaughan, J H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3091636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112631
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