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Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.

Synovial fluid mononuclear cells (SFMC) from patients with active rheumatoid arthritis characteristically respond poorly to mitogens. In this study, mitogenic antibodies reactive with the CD3(T3) antigen on human T lymphocytes were used to analyze the basis for the deficiency. OKT3-induced prolifera...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Lotz, M, Tsoukas, C D, Robinson, C A, Dinarello, C A, Carson, D A, Vaughan, J H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423658/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3091636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112631
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