Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice

BACKGROUND: Theiler’s murine encephalomyelitis virus (TMEV) infection represents a commonly used infectious animal model to study various aspects of the pathogenesis of multiple sclerosis (MS). In susceptible SJL mice, dominant activity of Foxp3(+) CD4(+) regulatory T cells (Tregs) in the CNS partly...

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Publicado en:J Neuroinflammation
Autores principales: Prajeeth, Chittappen K, Beineke, Andreas, Iskandar, Cut Dahlia, Gudi, Viktoria, Herder, Vanessa, Gerhauser, Ingo, Haist, Verena, Teich, René, Huehn, Jochen, Baumgärtner, Wolfgang, Stangel, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236492/
https://ncbi.nlm.nih.gov/pubmed/25391297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0180-9
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