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Reciprocal Changes in Vanilloid (TRPV1) and Endocannabinoid (CB1) Receptors Contribute to Visceral Hyperalgesia in the Water Avoidance Stressed Rat

BACKGROUND: Increasing evidence suggests that chronic stress plays an important role in the pathophysiology of several functional gastrointestinal disorders. We investigated whether CB1 and TRPV1 receptors are involved in stress induced visceral hyperalgesia. METHODS: Male rats were exposed to 1-hou...

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Publicat a:Gut
Autors principals: Hong, Shuangsong, Fan, Jing, Kemmerer, Elyse S., Evans, Simon, Li, Ying, Wiley, John W.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236191/
https://ncbi.nlm.nih.gov/pubmed/18936104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2008.157594
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